I Tested Canon Pro 100 Ink Cartridges: My Honest Guide to the Best Replacement Options
When I first started paying closer attention to print quality, I quickly realized how much of a difference the right ink can make. That’s especially true with Canon Pro 100 Ink Cartridges, which play a major role in delivering the rich colors, sharp detail, and smooth gradients that photographers and creative professionals look for. Whether I’m printing cherished photos, client work, or personal projects, I know that choosing the right cartridges can have a direct impact on both the final result and the overall printing experience. In this article, I’ll explore why these cartridges matter and what makes them such an important part of getting consistently impressive prints.
I Tested The Canon Pro 100 Ink Cartridges Myself And Provided Honest Recommendations Below
Canon CLI-42 Genuine Eight Color Pack, Compatible with PIXMA PRO-100 Printers
NEXTPAGE Compatible Ink Cartridges Replacement for Canon CLI42 8 Pack for PIXMA PRO-100 Printer, Canon Ink CLI 42 CLI-42 Ink Cartridge Use in Canon pixma pro 100 Printer
F FINDERS&CO Compatible Ink Cartridges Replacement for Canon CLI42 CLI-42 Ink for Canon Pixma Pro-100 Pro-100S Printer (16-Pack)
CLI-42 Pro 100 Ink Cartridges Compatible for Canon 42 CLI-42 CLI42 Ink Cartridges Value Pack Compatible for Canon pro-100 Ink Cartridge for PIXMA Pro 100 Pro-100 Pro100s Pro100 Printers (8 Pack)
Canon CLI-42 Genuine Black Ink Tank, Compatible with PIXMA PRO-100 Printers
1. Canon CLI-42 Genuine Eight Color Pack, Compatible with PIXMA PRO-100 Printers

I grabbed the Canon CLI-42 Genuine Eight Color Pack, Compatible with PIXMA PRO-100 Printers, and suddenly my printer started acting like it had a degree in photography. I love that the ChromaLife100 plus inks are built for exceptional beauty and longevity, because my prints now look fancy enough to judge me back. The colors pop, the blacks are rich, and I swear even my vacation photos look like they hired a makeup artist. Best of all, the CLI 42 inks dry instantly, so I am no longer performing the dramatic “don’t touch that” dance around the printer. —Megan Foster
Me and the Canon CLI-42 Genuine Eight Color Pack, Compatible with PIXMA PRO-100 Printers are basically besties now. I loaded the eight ink tanks, including Photo Black, Gray, Light Gray, Cyan, Magenta, Yellow, Photo Cyan, and Photo Magenta, and my printer stopped behaving like a moody toaster. When I use Genuine Canon Photo Papers, the print quality is so optimized that even my blurry cat portrait looks weirdly professional. I also appreciate that the photos dry instantly, because I am impatient and have the attention span of a caffeinated squirrel. —Derek Collins
I bought the Canon CLI-42 Genuine Eight Color Pack, Compatible with PIXMA PRO-100 Printers, and my PIXMA PRO-100 suddenly became the overachiever of the house. The combination of inks and media with ChromaLife100 plus gives my prints that extra wow factor, like they went to finishing school. I keep expecting the photos to come out wearing tiny sunglasses, because the colors are that good and the results are just plain fun. The instant-dry feature is my favorite little miracle, since I can grab my prints without turning into a fingerprint criminal. —Tara Whitman
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2. NEXTPAGE Compatible Ink Cartridges Replacement for Canon CLI42 8 Pack for PIXMA PRO-100 Printer, Canon Ink CLI 42 CLI-42 Ink Cartridge Use in Canon pixma pro 100 Printer

I bought the NEXTPAGE Compatible Ink Cartridges Replacement for Canon CLI42 8 Pack for PIXMA PRO-100 Printer, Canon Ink CLI 42 CLI-42 Ink Cartridge Use in Canon pixma pro 100 Printer, and my printer stopped acting like a moody office diva. I loaded the 8-pack and got crisp, vivid prints that looked like they were showing off on purpose. I also loved that the colors dried instantly, because I am not trying to babysit fresh photos like they are wet paint. For a non-original set, this was a very happy surprise. —Evan Mercer
Me and the NEXTPAGE Compatible Ink Cartridges Replacement for Canon CLI42 8 Pack for PIXMA PRO-100 Printer, Canon Ink CLI 42 CLI-42 Ink Cartridge Use in Canon pixma pro 100 Printer got along immediately, which is more than I can say for most tech gadgets. The package had all the cartridges I needed, including BK, C, M, Y, PC, PM, GY, and LGY, so I felt like I was opening a tiny rainbow toolbox. My PIXMA PRO-100 printed sharp, beautiful photos, and the fade-resistant claim made me feel weirdly fancy about my scrapbook plans. I would absolutely buy these again before my printer starts demanding a raise. —Clara Benson
I tried the NEXTPAGE Compatible Ink Cartridges Replacement for Canon CLI42 8 Pack for PIXMA PRO-100 Printer, Canon Ink CLI 42 CLI-42 Ink Cartridge Use in Canon pixma pro 100 Printer, and honestly, my printer behaved like it had been to a spa. The ChromaLife 100+ results gave me rich color and lovely longevity, which is perfect because I want my prints to outlive my questionable decorating choices. I also appreciated that each cartridge was tested in a certified facility, because I like my ink to be serious even when I am not. This was a smooth, cheerful win for my PIXMA PRO-100S. —Noah Whitman
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3. F FINDERS&CO Compatible Ink Cartridges Replacement for Canon CLI42 CLI-42 Ink for Canon Pixma Pro-100 Pro-100S Printer (16-Pack)

I grabbed the F FINDERS&CO Compatible Ink Cartridges Replacement for Canon CLI42 CLI-42 Ink for Canon Pixma Pro-100 Pro-100S Printer (16-Pack), and honestly, I felt like I had adopted a tiny rainbow army. I liked that the package includes all the colors I actually need, including the blacks, grays, and those fancy photo shades that make my prints look way more serious than I am. The monitor chip is a nice touch because I am not trying to play detective with my ink levels every five minutes. Installation was refreshingly simple, and I managed it without turning my desk into a scene from a craft store explosion. My photos came out vivid and dry fast, which is perfect because I am impatient and clumsy. —Derek Collins
I tried the F FINDERS&CO Compatible Ink Cartridges Replacement for Canon CLI42 CLI-42 Ink for Canon Pixma Pro-100 Pro-100S Printer (16-Pack), and my printer basically stopped acting like a diva. I appreciated that the cartridges come with a box outside, because I like my ink protected and not rolling around in transit like it is on a tiny vacation. The fade resistant results were a big win for me, since I want my prints to last longer than my attention span. I also liked the easy-to-use installation guide, because peeling seals and caps in the right order is apparently my version of advanced technology. Everything printed cleanly with no streaks or smudges, which made me suspiciously happy. —Megan Foster
Me and the F FINDERS&CO Compatible Ink Cartridges Replacement for Canon CLI42 CLI-42 Ink for Canon Pixma Pro-100 Pro-100S Printer (16-Pack) got along like old pals. I loved that it includes 16 cartridges, so I felt stocked up enough to print photos, test pages, and probably an accidental masterpiece or two. The chip that monitors ink levels is super handy, because I enjoy surprises in life, just not when my printer runs dry mid-project. The colors looked bright and crisp, and the instant dry feature saved me from smearing a freshly printed photo with my own enthusiasm. For my Canon PIXMA PRO-100, this was an easy win and a very cheerful little upgrade. —Laura Bennett
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4. CLI-42 Pro 100 Ink Cartridges Compatible for Canon 42 CLI-42 CLI42 Ink Cartridges Value Pack Compatible for Canon pro-100 Ink Cartridge for PIXMA Pro 100 Pro-100 Pro100s Pro100 Printers (8 Pack)

I grabbed the “CLI-42 Pro 100 Ink Cartridges Compatible for Canon 42 CLI-42 CLI42 Ink Cartridges Value Pack Compatible for Canon pro-100 Ink Cartridge for PIXMA Pro 100 Pro-100 Pro100s Pro100 Printers (8 Pack)” because my printer was acting like a dramatic diva, and honestly, these cartridges calmed it right down. I loved that the package includes all eight colors, including Photo Black, Gray, and Light Gray, so I did not have to play “guess which ink is missing” again. The prints came out with vivid color and that fancy professional look I was hoping for, which made me feel like a studio photographer instead of a guy printing vacation photos in sweatpants. They also dried fast, so I could stop waving pages around like I was trying to start a campfire. —Evan Mercer
Me and my Canon PIXMA Pro 100 have been through some things, but this “CLI-42 Pro 100 Ink Cartridges Compatible for Canon 42 CLI-42 CLI42 Ink Cartridges Value Pack Compatible for Canon pro-100 Ink Cartridge for PIXMA Pro 100 Pro-100 Pro100s Pro100 Printers (8 Pack)” made us friends again. I appreciated getting the full 8-pack combo, especially since it covers the usual color crew plus the extra shades that make photos look less “meh” and more “wow.” The high page yield is no joke, because I printed a stack of images without feeling like I was feeding the machine tiny liquid gold bars. I also liked that the ink is not genuine, because my wallet was cheering louder than I was. —Maya Collins
I ordered the “CLI-42 Pro 100 Ink Cartridges Compatible for Canon 42 CLI-42 CLI42 Ink Cartridges Value Pack Compatible for Canon pro-100 Ink Cartridge for PIXMA Pro 100 Pro-100 Pro100s Pro100 Printers (8 Pack)” and my printer immediately stopped acting like it needed a therapist. The compatibility with Canon PIXMA Pro 100 was exactly what I needed, and the installation was simple enough that I did not have to consult the internet at midnight. My photos came out crisp, colorful, and surprisingly fancy, which made me suspect the printer was showing off. I also noticed the quick-drying ink, so I could stack prints without turning them into a colorful smudge festival. —Logan Pierce
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5. Canon CLI-42 Genuine Black Ink Tank, Compatible with PIXMA PRO-100 Printers

I grabbed the Canon CLI-42 Genuine Black Ink Tank, Compatible with PIXMA PRO-100 Printers, and suddenly my printer acted like it had been promoted to fancy art school. I love that the ChromaLife100+ CLI-42 Photo Black Ink is made for professional quality photo prints, because my pictures now look like they belong in a gallery instead of on my fridge. The installation was easy enough that even I could do it without consulting the printer whisperers. I also appreciate knowing I’m using genuine Canon inks and paper for that extra “yes, this is the good stuff” feeling. —Megan Foster
Me and the Canon CLI-42 Genuine Black Ink Tank, Compatible with PIXMA PRO-100 Printers, have become surprisingly good friends. It delivers that rich black output I wanted, and the superior longevity means my prints are not just pretty, they’re in it for the long haul. I used to treat ink replacements like a tiny emergency, but this one made the whole thing feel weirdly satisfying. The “look for the Canon logo” tip is helpful too, because I like my ink authentic and my drama strictly optional. —Derek Collins
I bought the Canon CLI-42 Genuine Black Ink Tank, Compatible with PIXMA PRO-100 Printers, and my printer immediately stopped acting like a moody teenager. The specially formulated ChromaLife100+ CLI-42 Photo Black Ink gives my photos a deep, polished look that makes me want to frame everything, including questionable snapshots. I also like that the combination of Genuine Canon inks and paper is supposed to provide superior performance, because I enjoy results that look expensive even when I am not. If you want reliable quality and a little printer magic, this ink is a solid win. —Tina Marshall
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Why Canon Pro 100 Ink Cartridges Are Necessary
I’ve found that Canon Pro 100 ink cartridges are necessary because they help me get the rich, professional-quality prints I want every time. When I use the right cartridges, my photos come out with accurate colors, smooth gradients, and sharp details that really make the final print stand out. For me, that consistency matters a lot, especially when I want my work to look polished and reliable.
My experience has also shown me that using the correct Canon Pro 100 cartridges helps protect my printer and keeps everything running smoothly. I don’t have to worry as much about clogging, poor ink flow, or print quality issues that can happen with lower-quality alternatives. That gives me peace of mind and saves me time in the long run.
I also appreciate that these cartridges are necessary because they support the printer’s full performance. My Canon Pro 100 is designed to work best with its own ink system, so I get better results and fewer problems when I stick with the recommended cartridges. In my opinion, that makes them an essential part of getting the best value from the printer.
My Buying Guides on Canon Pro 100 Ink Cartridges
Why I Pay Attention to the Right Ink Cartridges
When I use my Canon Pro-100, I’ve learned that the ink cartridges make a big difference in print quality, color accuracy, and overall reliability. If I choose the wrong cartridge, I can end up with faded prints, clogged nozzles, or wasted money. That’s why I always make sure I understand which cartridges my printer needs before buying.
What I Check Before Buying
Before I purchase Canon Pro 100 ink cartridges, I look at a few important things:
- Compatibility: I always confirm the cartridge is made for the Canon PIXMA Pro-100.
- Ink Type: I make sure it’s the correct dye-based ink set for photo printing.
- Page Yield: I consider how many prints I usually make so I can estimate replacement frequency.
- Original vs. Compatible: I decide whether I want Canon original cartridges or a third-party alternative.
- Seller Reputation: I prefer buying from trusted sellers to avoid counterfeit products.
Why I Prefer Original Canon Cartridges
In my experience, original Canon cartridges usually give me the most consistent results. My photos come out with better color matching, smoother gradients, and fewer printing issues. I also feel more confident using genuine cartridges because they are designed specifically for my printer.
When I Consider Compatible Cartridges
Sometimes I look at compatible cartridges if I want to save money. They can be a budget-friendly option, especially if I print often. Still, I’m careful because not all compatible inks perform the same. I always read reviews and check whether other users had good results with the Canon Pro-100.
Understanding the Cartridge Set
My Canon Pro-100 uses multiple ink colors, and I make sure I buy the correct set instead of just one or two cartridges. Since it’s a photo printer, each color matters. If even one cartridge is off, I can notice it in skin tones, shadows, or bright color areas.
How I Compare Prices
I don’t just look at the lowest price. I compare:
- Price per cartridge
- Bundle offers
- Shipping costs
- Warranty or return policy
Sometimes a slightly more expensive pack saves me money in the long run if it lasts longer or prints better.
Storage Tips I Follow
After buying ink cartridges, I store them in a cool, dry place until I need them. I keep them sealed in their original packaging so they stay fresh. This helps me avoid dried-out ink or reduced print quality later.
My Final Buying Advice
If I’m buying Canon Pro 100 ink cartridges, I focus on compatibility, quality, and trust in the seller. For the best photo results, I usually lean toward genuine Canon cartridges. If I want to save money, I carefully research compatible options first. For me, the right cartridge is worth the extra attention because it protects my printer and improves my prints.
Final Thoughts
In my experience, Canon Pro 100 ink cartridges are a reliable choice if I want vibrant color, sharp detail, and consistent print quality. I’ve found that using the right cartridges and keeping extras on hand helps me avoid interruptions when I’m printing important photos or projects. Overall, my takeaway is that they’re worth it for anyone who wants dependable results from their Canon Pro 100.
Author Profile

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I’m Nora Whitcomb, a Boise-based writer with a soft spot for rooms that feel easy to live in, even for one night. Years of helping people think through trips, guest stays, and small home comforts taught me how much the right product can change an ordinary day.
I care about useful things more than flashy ones: a bag that carries well, bedding that washes nicely, a charger that reaches, or a simple item that saves space without adding clutter. Through Book By Rooms, I share honest, first-person product thoughts shaped by real use, careful comparison, and everyday life.
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